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GeneQ18028418· pop 5· linked from 6 articles

KTN1

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Also known as CG1, KNT, MU-RMS-40.19, kinectin 1

Kinectin is a protein that in humans is encoded by the KTN1 gene.

In the Vinony graph

Within Vinony's link graph, KTN1 is referenced by 6 other articles, and connects out to Q180686, human chromosome 14 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 14.

Its subject is documented across 5 Wikipedia language editions.

Gene data

KTN1

Name: kinectin 1
Type: protein-coding
Position: 55,559,072–55,701,526 (+)
Aliases: CG1, KNT, MU-RMS-40.19
Ensembl: ENSG00000126777
RefSeq RNA: NM_001079521.2, NM_001079522.2, NM_001271014.2, NM_001402682.1, NM_001402683.1
RefSeq protein: NP_001072989.1, NP_001072990.1, NP_001257943.1, NP_001389611.1, NP_001389612.1

This gene encodes an integral membrane protein that is a member of the kinectin protein family. The encoded protein is primarily localized to the endoplasmic reticulum membrane. This protein binds kinesin and may be involved in intracellular organelle motility. This protein also binds translation elongation factor-delta and may be involved in the assembly of the elongation factor-1 complex. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Aug 2012].

Gene Ontology

Biological process

microtubule-based movement microtubule-based movement protein transport

Molecular function

RNA binding protein binding kinesin binding cadherin binding

Cellular component

endoplasmic reticulum endoplasmic reticulum lumen endoplasmic reticulum membrane endoplasmic reticulum membrane plasma membrane membrane membrane

Pathways

Signal Transduction Signaling by Rho GTPases RHO GTPase Effectors Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)Metabolism of proteins RHO GTPases activate KTN1 Post-translational protein modification Post-translational protein phosphorylation RHOA GTPase cycle RHO GTPase cycle

via MyGene.info

Gene · Ensembl

kinectin 1

Symbol: KTN1
Biotype: Protein coding
Organism: Homo sapiens
Location: 14:55,559,072-55,701,526
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts

HomoloGene ID: 135663
exact match: identifiers.org/ncbigene/3895
genomic end: 56168244
genomic start: 56025790
cytogenetic location: 14q22.3

Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

4 sections

Contents

Function
Interactions
References
Further reading

Kinectin is a protein that in humans is encoded by the KTN1 gene.

== Function ==

Excerpted from Wikipedia’s “KTN1” article, available under the CC BY-SA 4.0 licence.

Available in 5 languages

via Wikidata sitelinks · CC0

Categories

Genes on human chromosome 14