EEF1D

Name

eukaryotic translation elongation factor 1 delta

Type

protein-coding

Position

143,579,697–143,599,541 (−)

Aliases

EF-1D, EF1D, FP1047, NEDTCHAL

Ensembl

ENSG00000273594

RefSeq RNA

NM_001130053.5, NM_001130054.1, NM_001130055.4, NM_001130056.5, NM_001130057.4

RefSeq protein

NP_001123525.3, NP_001123527.1, NP_001123528.1, NP_001123529.1, NP_001182132.1

This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit, delta, functions as guanine nucleotide exchange factor. It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat. This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.[provided by RefSeq, Aug 2010].

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Gene · Ensembl

eukaryotic translation elongation factor 1 delta

Symbol

EEF1D

Biotype

Protein coding

Organism

Homo sapiens

Location

8:143,579,697-143,599,541

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

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