MRPL23

Name

mitochondrial ribosomal protein L23

Type

protein-coding

Position

1,947,278–2,014,943 (+)

Aliases

L23MRP, L23mt, MRP-L23, RPL23L, uL23m

Ensembl

ENSG00000288141

RefSeq RNA

NM_001400172.1, NM_001400174.1, NM_001400176.1, NM_001400179.1, NM_001400182.1

RefSeq protein

NP_001387101.1, NP_001387103.1, NP_001387105.1, NP_001387108.1, NP_001387111.1

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. The gene is biallelically expressed, despite its location within a region of imprinted genes on chromosome 11. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

mitochondrial ribosomal protein L23

Symbol

MRPL23

Biotype

Protein coding

Organism

Homo sapiens

Location

11:1,947,278-2,014,943

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

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