MRPL10

Name

mitochondrial ribosomal protein L10

Type

protein-coding

Position

47,823,272–47,831,545 (−)

Aliases

L10MT, MRP-L10, MRP-L8, MRPL8, RPML8, uL10m

Ensembl

ENSG00000159111

RefSeq RNA

NM_145255.4, NM_148887.3, NR_037575.2, XM_024450575.2, XM_054315044.1

RefSeq protein

NP_660298.2, NP_683685.1, XP_024306343.1, XP_054171019.1

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode two different isoforms. A pseudogene corresponding to this gene is found on chromosome 5q. [provided by RefSeq, Nov 2010].

via MyGene.info

Gene · Ensembl

mitochondrial ribosomal protein L10

Symbol

MRPL10

Biotype

Protein coding

Organism

Homo sapiens

Location

17:47,823,272-47,831,545

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

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