EIF2B5
Sign in to saveAlso known as CACH, CLE, EIF-2B, EIF2Bepsilon, LVWM, eukaryotic translation initiation factor 2B subunit epsilon
Translation initiation factor eIF-2B subunit epsilon is a protein that in humans is encoded by the EIF2B5 gene.
Gene data
EIF2B5- Name
- eukaryotic translation initiation factor 2B subunit epsilon
- Type
- protein-coding
- Position
- 184,134,986–184,146,127 (+)
- Aliases
- CACH, CLE, EIF-2B, EIF2Bepsilon, LVWM, VWM5
- Ensembl
- ENSG00000145191
- RefSeq RNA
- NM_003907.3, XM_011513265.1, XM_011513266.4, XM_047449148.1, XM_054348280.1
- RefSeq protein
- NP_003898.2, XP_011511567.1, XP_011511568.1, XP_047305104.1, XP_054204255.1
This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter. [provided by RefSeq, Nov 2009].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
eukaryotic translation initiation factor 2B subunit epsilon
- Symbol
- EIF2B5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:184,134,986-184,146,127
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 2903
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/8893
- genomic end
- 184146127
- genomic start
- 183852826
- chromosome
- human chromosome 3
- cytogenetic location
- 3q27.1
- genetic association
- leukoencephalopathy with vanishing white matter
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
Translation initiation factor eIF-2B subunit epsilon is a protein that in humans is encoded by the EIF2B5 gene.
== Interactions ==
Excerpted from Wikipedia’s “EIF2B5” article, available under the CC BY-SA 4.0 licence.