MRPL24

Also known as L24mt, MRP-L18, MRP-L24, mitochondrial ribosomal protein L24

protein-coding gene in the species Homo sapiens

Gene data

MRPL24

Name: mitochondrial ribosomal protein L24
Type: protein-coding
Aliases: L24mt, MRP-L18, MRP-L24, uL24m

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which is more than twice the size of its E.coli counterpart (EcoL24). Sequence analysis identified two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008].

via MyGene.info