MRPL12

Name

mitochondrial ribosomal protein L12

Type

protein-coding

Position

81,703,357–81,711,112 (+)

Aliases

5c5-2, L12mt, MRP-L31/34, MRPL7, MRPL7/L12, RPML12, bL12m

Ensembl

ENSG00000262814

RefSeq RNA

NM_002949.4

RefSeq protein

NP_002940.2

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which forms homodimers. In prokaryotic ribosomes, two L7/L12 dimers and one L10 protein form the L8 protein complex. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

mitochondrial ribosomal protein L12

Symbol

MRPL12

Biotype

Protein coding

Organism

Homo sapiens

Location

17:81,703,357-81,711,112

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

PBB Protein MRPL11 image.jpg

via Wikidata · CC0