MRPL32

Also known as L32mt, MRP-L32, bMRP-59b, HSPC283, mitochondrial ribosomal protein L32

protein-coding gene in the species Homo sapiens

Gene data

MRPL32

Name: mitochondrial ribosomal protein L32
Type: protein-coding
Position: 42,932,346–42,948,958 (+)
Aliases: HSPC283, L32mt, MRP-L32, bL32m, bMRP-59b
Ensembl: ENSG00000106591
RefSeq RNA: NM_031903.3, NR_156497.1
RefSeq protein: NP_114109.1

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L32 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome Xp. [provided by RefSeq, Jul 2008].