RHOA

Name

ras homolog family member A

Type

protein-coding

Position

49,359,136–49,412,998 (−)

Aliases

ARH12, ARHA, EDFAOB, RHO12, RHOH12

Ensembl

ENSG00000067560

RefSeq RNA

NM_001313941.2, NM_001313943.2, NM_001313944.2, NM_001313945.2, NM_001313946.2

RefSeq protein

NP_001300870.1, NP_001300872.1, NP_001300873.1, NP_001300874.1, NP_001300875.1

This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015].

via MyGene.info

Gene · Ensembl

ras homolog family member A

Symbol

RHOA

Biotype

Protein coding

Organism

Homo sapiens

Location

3:49,359,136-49,412,998

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein RHOA PDB 1a2b.png

via Wikidata · CC0