LALBA
Sign in to saveAlso known as entrez:3906, LYZG, lactalbumin alpha, HAMLET
α-lactalbumin, also known as alpha-lactalbumin and LALBA, is a protein that in humans is encoded by the LALBA gene.
Gene data
LALBA- Name
- lactalbumin alpha
- Type
- protein-coding
- Position
- 48,567,684–48,571,865 (−)
- Aliases
- HAMLET, LYZG
- Ensembl
- ENSG00000167531
- RefSeq RNA
- NM_001384350.1, NM_002289.3
- RefSeq protein
- NP_001371279.1, NP_002280.1
This gene encodes alpha-lactalbumin, a principal protein of milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and beta 1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transfering galactose moieties to glucose. As a monomer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of alpha-lactalbumin, called HAMLET, likely induces apoptosis in tumor and immature cells. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
lactalbumin alpha
- Symbol
- LALBA
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:48,567,684-48,571,865
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~6 min read
Encyclopedic overview
12 sectionsContents
- Overview
- Physical properties
- Evolution
- Functions
- Nutrition
- Clinical Uses
- PCOS
- Mental health
- Cancer
- References
- Further reading
- External links
α-lactalbumin, also known as alpha-lactalbumin and LALBA, is a protein that in humans is encoded by the LALBA gene.
== Overview ==
Excerpted from Wikipedia’s “LALBA” article, available under the CC BY-SA 4.0 licence.