laminitis

thumb|300px|Radiograph of a horse hoof showing marked separation of the hoof from the coffin bone with evidence of rotation and sinking, comaptible with active severe laminitis. P2 designates the middle phalanx, or [[pastern bone, and P3 designates the distal phalanx, or coffin bone. The yellow lines mark the distance between the top and bottom part of the coffin bone relative to the hoof wall, showing marked widening of the hoof-lamellar zone, with the distal (bottom) of the coffin bone rotated away from the hoof wall.]]

Laminitis is a disease of the feet of ungulates, found mostly in horses and cattle involving inflammation of the laminae. Clinical signs include foot tenderness progressing to inability to walk, increased digital pulses, and increased temperature in the hooves. Severe cases with outwardly visible clinical signs are known by the colloquial term founder, and progression of the disease will lead to perforation of the coffin bone through the sole of the hoof or being unable to stand up, often requiring euthanasia.