lipodystrophy

Lipodystrophy syndromes are a group of genetic or acquired disorders in which the body is unable to produce and maintain healthy fat tissue. The medical condition is characterized by abnormal or degenerative conditions of the body's adipose tissue. A more specific term, lipoatrophy (), is used when describing the loss of fat from one area (usually the face). This condition is also characterized by a lack of circulating leptin which may lead to osteosclerosis. The absence of fat tissue is associated with insulin resistance, hypertriglyceridemia, non-alcoholic fatty liver disease (NAFLD) and metabolic syndrome.

== Types == Lipodystrophy can be divided into the following types: Congenital lipodystrophy syndromes Congenital generalized lipodystrophy (Berardinelli-Seip syndrome) Familial partial lipodystrophy Marfanoid–progeroid–lipodystrophy syndrome Chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature syndrome Acquired lipodystrophy syndromes Acquired partial lipodystrophy (Barraquer-Simons syndrome) Acquired generalized lipodystrophy Centrifugal abdominal lipodystrophy (lipodystrophia centrifugalis abdominalis infantilis) Lipoatrophia annularis (Ferreira-Marques lipoatrophia) Localized lipodystrophy HIV-associated lipodystrophy