LORICRIN
Sign in to saveAlso known as LOR, loricrin cornified envelope precursor protein
Loricrin is a protein that in humans is encoded by the LOR gene.
Gene data
LORICRIN- Name
- loricrin cornified envelope precursor protein
- Type
- protein-coding
- Position
- 153,259,687–153,262,124 (+)
- Aliases
- LOR
- Ensembl
- ENSG00000203782
- RefSeq RNA
- NM_000427.3
- RefSeq protein
- NP_000418.2
This gene encodes loricrin, a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells. Mutations in this gene are associated with Vohwinkel's syndrome and progressive symmetric erythrokeratoderma, both inherited skin diseases. [provided by RefSeq, Jul 2008].
Gene Ontology
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
loricrin cornified envelope precursor protein
- Symbol
- LORICRIN
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:153,259,687-153,262,124
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/4014
- genomic end
- 153262124
- genomic start
- 153259687
- chromosome
- human chromosome 1
- cytogenetic location
- 1q21.3
- expressed in
- amniotic fluid
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Clinical significance
- See also
- References
- Further reading
Loricrin is a protein that in humans is encoded by the LOR gene.
== Function == Loricrin is a major protein component of the cornified cell envelope found in terminally differentiated epidermal cells.
Excerpted from Wikipedia’s “LORICRIN” article, available under the CC BY-SA 4.0 licence.