Structure via PubChem · Public domain (PubChem)
lufenuron
Sign in to saveAlso known as N-((2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)carbamoyl)-2,6-difluorobenzamide, N-({[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]amino}carbonyl)-2,6-difluorobenzamide, 1-(2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)-3-(2,6-difluorobenzoyl)urea, Fluphenacur
Lufenuron is the active ingredient in the veterinary flea control medication program, and one of the two active ingredients in the flea, heartworm, and anthelmintic medicine milbemycin oxime/lufenuron (Sentinel).
Chemical data
- Formula
- C17H8Cl2F8N2O3
- Molecular weight
- 511.1 g/mol
- IUPAC name
- N-[[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl]-2,6-difluorobenzamide
- SMILES
- C1=CC(=C(C(=C1)F)C(=O)NC(=O)NC2=CC(=C(C=C2Cl)OC(C(C(F)(F)F)F)(F)F)Cl)F
- InChIKey
- PWPJGUXAGUPAHP-UHFFFAOYSA-N
- XLogP
- 6.4
- Polar surface area
- 67.4 Ų
- H-bond donors
- 2
- H-bond acceptors
- 11
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
284 papers- Dissecting the manipulation of lufenuron on chitin synthesis in Helicoverpa armigera.Pesticide biochemistry and physiology · 2024
- Amlodipine and lufenuron as repurposing drugs against Sporothrix brasiliensis.PeerJ · 2023
- EVALUATING BAITS WITH LUFENURON AND NITENPYRAM FOR FLEA CONTROL ON PRAIRIE DOGS (CYNOMYS SPP.) TO MITIGATE PLAGUE.Journal of wildlife diseases · 2023
- Detection of Chitin Synthase Mutations in Lufenuron-Resistant Spodoptera frugiperda in China.Insects · 2022
- Effects of lufenuron treatments on the growth and development of Spodoptera frugiperda (Lepidoptera: Noctuidae).Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2023
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 509.978
- Has use
- insecticide
Show 3 more facts
- chemical formula
- C₁₇H₈Cl₂F₈N₂O₃
- canonical SMILES
- C1=CC(=C(C(=C1)F)C(=O)NC(=O)NC2=CC(=C(C=C2Cl)OC(C(C(F)(F)F)F)(F)F)Cl)F
- Commons category
- Lufenuron
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- External links
Lufenuron is the active ingredient in the veterinary flea control medication program, and one of the two active ingredients in the flea, heartworm, and anthelmintic medicine milbemycin oxime/lufenuron (Sentinel).
Lufenuron is stored in the animal's body fat and transferred to adult fleas through the host's blood when they feed. Adult fleas transfer it to their growing eggs through their blood, and to hatched larvae feeding on their excrement. It does not kill adult fleas.
Excerpted from Wikipedia’s “lufenuron” article, available under the CC BY-SA 4.0 licence.