Structure via PubChem · Public domain (PubChem)
ルフェヌロン
Sign in to saveAlso known as N-((2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)carbamoyl)-2,6-difluorobenzamide, Lufenuron, N-({[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]amino}carbonyl)-2,6-difluorobenzamide, 1-(2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl)-3-(2,6-difluorobenzoyl)urea, Fluphenacur
Lufenuron is the active ingredient in the veterinary flea control medication program, and one of the two active ingredients in the flea, heartworm, and anthelmintic medicine milbemycin oxime/lufenuron (Sentinel).
Chemical data
- Formula
- C17H8Cl2F8N2O3
- Molecular weight
- 511.1 g/mol
- IUPAC name
- N-[[2,5-dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl]carbamoyl]-2,6-difluorobenzamide
- SMILES
- C1=CC(=C(C(=C1)F)C(=O)NC(=O)NC2=CC(=C(C=C2Cl)OC(C(C(F)(F)F)F)(F)F)Cl)F
- InChIKey
- PWPJGUXAGUPAHP-UHFFFAOYSA-N
- XLogP
- 6.4
- Polar surface area
- 67.4 Ų
- H-bond donors
- 2
- H-bond acceptors
- 11
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
284 papers- Dissecting the manipulation of lufenuron on chitin synthesis in Helicoverpa armigera.Pesticide biochemistry and physiology · 2024
- Amlodipine and lufenuron as repurposing drugs against Sporothrix brasiliensis.PeerJ · 2023
- EVALUATING BAITS WITH LUFENURON AND NITENPYRAM FOR FLEA CONTROL ON PRAIRIE DOGS (CYNOMYS SPP.) TO MITIGATE PLAGUE.Journal of wildlife diseases · 2023
- Detection of Chitin Synthase Mutations in Lufenuron-Resistant Spodoptera frugiperda in China.Insects · 2022
- Effects of lufenuron treatments on the growth and development of Spodoptera frugiperda (Lepidoptera: Noctuidae).Comparative biochemistry and physiology. Toxicology & pharmacology : CBP · 2023
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 509.978
- Has use
- insecticide
Show 3 more facts
- chemical formula
- C₁₇H₈Cl₂F₈N₂O₃
- canonical SMILES
- C1=CC(=C(C(=C1)F)C(=O)NC(=O)NC2=CC(=C(C=C2Cl)OC(C(C(F)(F)F)F)(F)F)Cl)F
- Commons category
- Lufenuron
via Wikidata · CC0
Article · 日本語
ルフェヌロン (lufenuron) とは、昆虫成長制御剤のひとつ。キチン質は節足動物の外骨格の構成成分であり、発育期に合成される。ルフェヌロンなどのキチン質合成阻害薬は、キチン質の合成を阻害することにより、幼虫の孵化および脱皮を阻害する。 報告されている融点、LD50値はそれぞれ 174 ℃、>2000 mg/kg（ラット、経口）。CAS登録番号は[103055-07-8]。
Abstract from DBpedia / Wikipedia · CC BY-SA