lyase
Sign in to saveAlso known as lyases
In biochemistry, a lyase is an enzyme that catalyzes the breaking (an elimination reaction) of various chemical bonds by means other than hydrolysis (a substitution reaction) and oxidation, often forming a new double bond or a new ring structure. The reverse reaction is also possible (called a Michael reaction). For example, an enzyme that catalyzed this reaction would be a lyase:
Research
168,277 papersvia PubMed
Wikidata facts
Show 2 more facts
- Commons category
- EC 4. Lyases
- EC enzyme number
- 4.-.-.-
Sources (2)
via Wikidata · CC0
~2 min read
Article
5 sectionsContents
- Nomenclature
- Classification
- Membrane-associated lyases
- See also
- References
In biochemistry, a lyase is an enzyme that catalyzes the breaking (an elimination reaction) of various chemical bonds by means other than hydrolysis (a substitution reaction) and oxidation, often forming a new double bond or a new ring structure. The reverse reaction is also possible (called a Michael reaction). For example, an enzyme that catalyzed this reaction would be a lyase: ATP → cAMP + PPi
Lyases differ from other enzymes in that they require only one substrate for the reaction in one direction, but two substrates for the reverse reaction.