Ferrochelatase
Also known as heme synthase, ferrochelatase, mitochondrial, heme synthetase, FECH, protoheme ferro-lyase, protoporphyria
Protoporphyrin ferrochelatase (EC 4.98.1.1, formerly EC 4.99.1.1, or ferrochelatase; systematic name protoheme ferro-lyase (protoporphyrin-forming)) is an enzyme encoded by the FECH gene in humans. Ferrochelatase catalyses the eighth and terminal step in the biosynthesis of heme, converting protoporphyrin IX into heme B. It catalyses the reaction:
Key facts
- Enzyme.align
- right
- Enzyme.name
- Protoporphyrin ferrochelatase
- Enzyme.image
- 1hrk.jpg
- Enzyme.image_size
- 270
- Enzyme.caption
- Ferrochelatase homodimer, Human
- Enzyme.EC_number
- 4.98.1.1
- Enzyme.CAS_number
- 9012-93-5
- Enzyme.GO_code
- 0004325
via Wikipedia infobox
~6 min read
Article
9 sectionsContents
- Function
- Structure
- Mechanism
- Clinical significance
- Interactions
- See also
- References
- Further reading
- External links
Protoporphyrin ferrochelatase (EC 4.98.1.1, formerly EC 4.99.1.1, or ferrochelatase; systematic name protoheme ferro-lyase (protoporphyrin-forming)) is an enzyme encoded by the FECH gene in humans. Ferrochelatase catalyses the eighth and terminal step in the biosynthesis of heme, converting protoporphyrin IX into heme B. It catalyses the reaction:
== Function ==