MAOA
Sign in to saveAlso known as MAO-A, monoamine oxidase A, BRNRS
protein-coding gene in the species Homo sapiens
Gene data
MAOA- Name
- monoamine oxidase A
- Type
- protein-coding
- Chromosome
- X
- Position
- 43,654,907–43,746,821 (+)
- Aliases
- BRNRS, MAO-A
- Ensembl
- ENSG00000189221
- RefSeq RNA
- NM_000240.4, NM_001270458.2
- RefSeq protein
- NP_000231.1, NP_001257387.1
This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012].
Gene Ontology
Biological process
Molecular function
Pathways
Glycine, serine and threonine metabolism - Homo sapiens (human)Arginine and proline metabolism - Homo sapiens (human)Histidine metabolism - Homo sapiens (human)Tyrosine metabolism - Homo sapiens (human)Phenylalanine metabolism - Homo sapiens (human)Tryptophan metabolism - Homo sapiens (human)Drug metabolism - cytochrome P450 - Homo sapiens (human)Serotonergic synapse - Homo sapiens (human)Dopaminergic synapse - Homo sapiens (human)Parkinson disease - Homo sapiens (human)
via MyGene.info
Gene · Ensembl
monoamine oxidase A
- Symbol
- MAOA
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr X:43,654,907-43,746,821
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Monoamine oxidase A 2BXS.png
Show 6 more facts
- HomoloGene ID
- 203
- Commons category
- Monoamine oxidase A
- exact match
- identifiers.org/ncbigene/4128
- genomic start
- 43515467
- genomic end
- 43746817
- cytogenetic location
- Xp11.3
Sources (9)
via Wikidata · CC0
Connections
mitochondrion
Entity
amine
Entity
Q180686
Entity
neurotransmitter
Entity
L-tyrosine
Entity
L-histidine
Entity
promoter
Entity
methylene blue
Entity
X chromosome
Entity
Enzyme Commission number
Entity
monoamine oxidase inhibitor
Entity
anti-social behaviour
Entity
Ensembl genome database project
Entity
3,4-dihydroxyphenylacetic acid
Entity
3-methoxy-4-hydroxyphenylglycol
Entity
MAOB
Gene
clorgiline
Entity
human
Entity
oxygen
Entity
Allium sativum
Entity