MAOA

Name

monoamine oxidase A

Type

protein-coding

Chromosome

X

Position

43,654,907–43,746,821 (+)

Aliases

BRNRS, MAO-A

Ensembl

ENSG00000189221

RefSeq RNA

NM_000240.4, NM_001270458.2

RefSeq protein

NP_000231.1, NP_001257387.1

This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012].