Structure via PubChem · Public domain (PubChem)
2C-B
Sign in to saveAlso known as 2,5-dimethoxy-4-bromophenethylamine, Nexus, 4-bromo-2,5-dimethoxyphenylethylamine, 4-bromo-2,5-dimethoxyphenethylamine, 2-(4-bromo-2,5-dimethoxyphenyl)ethylamine
2C-B, also known as 4-bromo-2,5-dimethoxyphenethylamine or by names such as Nexus or Erox, is a psychedelic drug of the phenethylamine and 2C families. The drug is used as a recreational drug and is usually taken orally. 2C-B produces hallucinogenic, mild stimulant, and mild entactogenic-like effects. Its hallucinogenic effects at typical doses are milder than those of other psychedelics like LSD or psilocybin.
Key facts
- Drug.image
- 2C-B.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 225px
- Drug.image2
- 2C-B-3d-sticks.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 200px
- Drug.tradename
- Erox; Nexus; Perfomax
- Drug.routes_of_administration
- Oral, insufflation
- Drug.class
- Serotonin receptor modulator; Serotonin 5-HT2A receptor agonist; Serotonergic psychedelic; Hallucinogen; stimulant; Entactogen
- Drug.ATC_prefix
- None
- Drug.legal_AU
- Schedule 9
- Drug.legal_BR
- F2
- Drug.legal_CA
- Schedule III
- Drug.legal_DE
- Anlage I
- Drug.legal_UK
- Class A
- Drug.legal_US
- Schedule I
- Drug.legal_UN
- P II
- Drug.bioavailability
- Low
via Wikipedia infobox
Chemical data
- Formula
- C10H14BrNO2
- Molecular weight
- 260.13 g/mol
- IUPAC name
- 2-(4-bromo-2,5-dimethoxyphenyl)ethanamine
- SMILES
- COC1=CC(=C(C=C1CCN)OC)Br
- InChIKey
- YMHOBZXQZVXHBM-UHFFFAOYSA-N
- XLogP
- 2.1
- Polar surface area
- 44.5 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Research
128 papers- Psilocybin and 2C-B at Encoding Distort Episodic Familiarity.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2024
- Acquired synaesthesia following 2C-B use.Psychopharmacology · 2019
- Tusi: a new ketamine concoction complicating the drug landscape.The American journal of drug and alcohol abuse · 2023
- Mistaking 2C-P for 2C-B: What a Difference a Letter Makes.Journal of analytical toxicology · 2017
- Acute pharmacological profile of 2C-B-Fly-NBOMe in male Wistar rats-pharmacokinetics, effects on behaviour and thermoregulation.Frontiers in pharmacology · 2023
via PubMed
Wikidata facts
- Mass
- 259.020791
- Image
- 2CBPowder.jpg
Show 3 more facts
- chemical formula
- C₁₀H₁₄BrNO₂
- canonical SMILES
- COC1=CC(=C(C=C1CCN)OC)Br
- Commons category
- 2C-B
via Wikidata · CC0
~30 min read
Article
51 sectionsContents
- Use and effects
- Contraindications
- Side effects
- Tolerance
- Long-term effects
- Overdose
- Interactions
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Absorption
- Distribution
- Metabolism
- Elimination
- Chemistry
- Synthesis
- Identification
- Analogues and derivatives
- History
- Society and culture
- Names
- Illicit forms
- Legal status
- United Nations
- Argentina
- Australia
- Belgium
- Brazil
- Canada
- Chile
- Czech Republic
- Denmark
- Estonia
- Finland
- Germany
- Italy
- Japan
- Luxembourg
- Netherlands
- Norway
- Poland
- Russia
- Spain
- Sweden
- Switzerland
- United Kingdom
- United States
- Research
- See also
- References
- External links
2C-B, also known as 4-bromo-2,5-dimethoxyphenethylamine or by names such as Nexus or Erox, is a psychedelic drug of the phenethylamine and 2C families. The drug is used as a recreational drug and is usually taken orally. 2C-B produces hallucinogenic, mild stimulant, and mild entactogenic-like effects. Its hallucinogenic effects at typical doses are milder than those of other psychedelics like LSD or psilocybin.
The drug acts as a potent partial agonist of the serotonin 5-HT2 receptors, including of the serotonin 5-HT2A receptor. It produces psychedelic-like effects in animals. Numerous analogues and derivatives of 2C-B are known, such as DOB, 2C-B-FLY, and 25B-NBOMe among others.