Structure via PubChem · Public domain (PubChem)
MEAI
Sign in to saveAlso known as 5-methoxy-2-indanamine, 5-methoxy-2-aminoindane, 5-MeO-AI, Chaperon
MEAI, also known as 5-methoxy-2-aminoindane (5-MeO-AI) and by its developmental code name CMND-100, is an entactogen-like psychoactive drug of the 2-aminoindane family. It is a cyclized phenethylamine and is the 2-aminoindane analogue of 3-methoxyamphetamine. The drug acts as a serotonin–norepinephrine releasing agent (SNRA) or as a modestly selective serotonin releasing agent (SSRA), with about 6-fold preference for induction of serotonin over norepinephrine release. MEAI has been encountered as a novel designer recreational drug. It is also under development for potential medical use in the
Chemical data
- Formula
- C10H13NO
- Molecular weight
- 163.22 g/mol
- IUPAC name
- 5-methoxy-2,3-dihydro-1H-inden-2-amine
- SMILES
- COC1=CC2=C(CC(C2)N)C=C1
- InChIKey
- HLXHCNWEVQNNKA-UHFFFAOYSA-N
- XLogP
- 1.3
- Polar surface area
- 35.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Wikidata facts
- Mass
- 163.099714
Show 2 more facts
- canonical SMILES
- COC1=CC2=C(CC(C2)N)C=C1
- chemical formula
- C₁₀H₁₃NO
Sources (2)
via Wikidata · CC0
~5 min read
Encyclopedic overview
11 sectionsContents
- Use and effects
- Interactions
- Pharmacology
- Pharmacodynamics
- Chemistry
- History
- Alcohol substitute
- Research
- See also
- References
- External links
MEAI, also known as 5-methoxy-2-aminoindane (5-MeO-AI) and by its developmental code name CMND-100, is an entactogen-like psychoactive drug of the 2-aminoindane family. It is a cyclized phenethylamine and is the 2-aminoindane analogue of 3-methoxyamphetamine. The drug acts as a serotonin–norepinephrine releasing agent (SNRA) or as a modestly selective serotonin releasing agent (SSRA), with about 6-fold preference for induction of serotonin over norepinephrine release. MEAI has been encountered as a novel designer recreational drug. It is also under development for potential medical use in the treatment of alcoholism, cocaine use disorder, metabolic syndrome, and obesity.
==Use and effects== When used recreationally, MEAI is reported to produce mild to moderate psychoactive effects, including stimulation and euphoria. Its dose is said to be 100 to 250mg orally and 30 to 60mg intranasally. The drug is sometimes used as an alcohol substitute.
Excerpted from Wikipedia’s “MEAI” article, available under the CC BY-SA 4.0 licence.