Structure via PubChem · Public domain (PubChem)
meclofenamic acid
Sign in to saveAlso known as CL-583, INF-4668, Meclomen®, INF 4668, N-(2,6-dichloro-m-tolyl)anthranilic acid, N-(3-methyl-2,6-dichlorophenyl)anthranilic acid, N-(2,6-dichloro-3-methylphenyl)anthranilic acid
chemical compound
Chemical data
- Formula
- C14H11Cl2NO2
- Molecular weight
- 296.1 g/mol
- IUPAC name
- 2-(2,6-dichloro-3-methylanilino)benzoic acid
- SMILES
- CC1=C(C(=C(C=C1)Cl)NC2=CC=CC=C2C(=O)O)Cl
- InChIKey
- SBDNJUWAMKYJOX-UHFFFAOYSA-N
- XLogP
- 5.2
- Polar surface area
- 49.3 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1980
- Admin. routes
- oral
- Indications
- rheumatic disease, Arthralgia, Myalgia
via ChEMBL · EBI
Research
1,224 papers- Repurposing auranofin and meclofenamic acid as energy-metabolism inhibitors and anti-cancer drugs.PloS one · 2024
- Proteomics analysis of meclofenamic acid-treated small cell lung carcinoma cells revealed changes in cellular energy metabolism for cancer cell survival.Journal of biochemical and molecular toxicology · 2023
- Meclofenamic acid selectively inhibits FTO demethylation of m6A over ALKBH5.Nucleic acids research · 2015
- Meclofenamic acid extends donor-recipient asynchrony in equine embryo transfer.Equine veterinary journal · 2006
- Recent acquisitions in pain therapy: meclofenamic acid.The Clinical journal of pain · 1991
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 295.017
- Has use
- medication
Show 7 more facts
- chemical formula
- C₁₄H₁₁Cl₂NO₂
- canonical SMILES
- CC1=C(C(=C(C=C1)Cl)NC2=CC=CC=C2C(=O)O)Cl
- World Health Organisation international non-proprietary name
- meclofenamic acid
- Commons category
- Meclofenamic acid
- medical condition treated
- inflammation
- subject has role
- non-steroidal anti-inflammatory drug
- physically interacts with
- Prostaglandin-endoperoxide synthase 2
Sources (2)
via Wikidata · CC0