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methylcholanthrene
EntityQ223099· pop 11· linked from 42 articles

methylcholanthrene

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Also known as 3-Methylcholanthrene

Methylcholanthrene is a highly carcinogenic polycyclic aromatic hydrocarbon produced by burning organic compounds at very high temperatures. Methylcholanthrene is also known as 3-methylcholanthrene, 20-methylcholanthrene or the IUPAC name 3-methyl-1,2-dyhydrobenzo[j]aceanthrylene. The short notation often used is 3-MC or MCA. This compound forms pale yellow solid crystals when crystallized from benzene and ether. It has a melting point around 180 °C and its boiling point is around 280 °C at a pressure of 80 mmHg. Methylcholanthrene is used in laboratory studies of chemical carcinogen

In the Vinony graph

Vinony's link graph records 42 inbound references to methylcholanthrene, and connects out to mass density, halogens and cholesterol.

It is catalogued under topics including Carcinogens, ECHA InfoCard ID from Wikidata and Hepatotoxins.

Vinony links it to 10 Wikipedia language editions.

Wikidata facts

Mass
268.125
Show 4 more facts
melting point
180
canonical SMILES
CC1=C2CCC3=C2C(=CC4=C3C=CC5=CC=CC=C54)C=C1
chemical formula
C₂₁H₁₆
Commons category
3-Methylcholanthrene
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via Wikidata · CC0

~8 min read

Encyclopedic overview

11 sections
Contents
  • History
  • Synthesis
  • Mechanism
  • Metabolism
  • Efficacy
  • Toxicity
  • Effects on animals
  • Effects on human
  • Non-human toxicity studies
  • References
  • External links

Methylcholanthrene is a highly carcinogenic polycyclic aromatic hydrocarbon produced by burning organic compounds at very high temperatures. Methylcholanthrene is also known as 3-methylcholanthrene, 20-methylcholanthrene or the IUPAC name 3-methyl-1,2-dyhydrobenzo[j]aceanthrylene. The short notation often used is 3-MC or MCA. This compound forms pale yellow solid crystals when crystallized from benzene and ether. It has a melting point around 180 °C and its boiling point is around 280 °C at a pressure of 80 mmHg. Methylcholanthrene is used in laboratory studies of chemical carcinogenesis. It is an alkylated derivative of [[benz(a)anthracene|benz[a]anthracene]] and has a similar UV spectrum. The most common isomer is 3-methylcholanthrene, although the methyl group can occur in other places.

3-Methylcholanthrene, a known carcinogen which builds up in the prostate due to cholesterol breakdown, is implicated in prostate cancer. It "readily produces" primary sarcomas in mice.

Excerpted from Wikipedia’s “methylcholanthrene” article, available under the CC BY-SA 4.0 licence.

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