methylenedioxyethamphetamine

Also known as N-ethyl-α-methyl-1,3-benzodioxole-5-ethanamine, 1,3-benzodioxole-5-ethanamine, N-ethyl-α-methyl-, MDEA, (+/-)-MDE, 3,4-methylenedioxy-N-ethylamphetamine, MDE, n-ethyl MDA, 3,4-Methylenedioxy-N-ethylamphetamine

'3,4-Methylenedioxy-N-ethylamphetamine (MDEA; also called MDE and colloquially, Eve') is an empathogenic psychoactive drug. MDEA is a substituted amphetamine and a substituted methylenedioxyphenethylamine. MDEA acts as a serotonin, norepinephrine, and dopamine releasing agent and reuptake inhibitor.

Key facts

Drug.legal_CA: Schedule I
Drug.drug_name: MDEA
Drug.image: MDEA structure.svg
Drug.image_class: skin-invert-image
Drug.width: 235px
Drug.image2: MDEA molecule ball.png
Drug.image_class2: bg-transparent
Drug.width2: 250px
Drug.routes_of_administration: Oral, insufflation, injection, rectal
Drug.class: Serotonin releasing agent; Entactogen
Drug.ATC_prefix: None
Drug.legal_AU: S9
Drug.legal_BR: F2
Drug.legal_DE: Anlage I
Drug.legal_UK: Class A
Drug.legal_US: Schedule I
Drug.legal_UN: Psychotropic Schedule I
Drug.CAS_number: 82801-81-8

via Wikipedia infobox

Research

186 papers

Hyperthermia associated with 3,4-methylenedioxyethamphetamine ('Eve').Anaesthesia · 1993
Sleep EEG effects of 3,4-methylenedioxyethamphetamine (MDE; "eve") in healthy volunteers.Biological psychiatry · 1992
The acute effect in rats of 3,4-methylenedioxyethamphetamine (MDEA, "eve") on body temperature and long term degeneration of 5-HT neurones in brain: a comparison with MDMA ("ecstasy").Pharmacology & toxicology · 1999
Intentional overdose and death with 3,4-methylenedioxyethamphetamine (MDEA; "Eve"): case report.The American journal of forensic medicine and pathology · 1998
Serotonin syndrome unmasking thyrotoxicosis.BMJ case reports · 2019

via PubMed

~3 min read

Encyclopedic overview

15 sections

Contents

Uses
Medical
Recreational
Adverse effects
Overdose
Interactions
Chemistry
Synthesis
History
Society and culture
Legal status
United States
See also
References
External links

Possession of MDEA is illegal in most countries. Some limited exceptions exist for scientific and medical research.

Excerpted from Wikipedia’s “methylenedioxyethamphetamine” article, available under the CC BY-SA 4.0 licence.

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