nadolol
Also known as Corgard®, corzide, SQ-11725
Nadolol, sold under the brand name Corgard among others, is a medication used to treat high blood pressure, heart pain, atrial fibrillation, and some inherited arrhythmic syndromes. It has also been used to prevent migraine headaches and complications of cirrhosis. It is taken orally.
Chemical data
- Formula
- C17H27NO4
- Molecular weight
- 309.4 g/mol
- IUPAC name
- (2R,3S)-5-[3-(tert-butylamino)-2-hydroxypropoxy]-1,2,3,4-tetrahydronaphthalene-2,3-diol
- SMILES
- CC(C)(C)NCC(COC1=CC=CC2=C1C[C@@H]([C@@H](C2)O)O)O
- InChIKey
- VWPOSFSPZNDTMJ-UCWKZMIHSA-N
- XLogP
- 0.7
- Polar surface area
- 82 Ų
- H-bond donors
- 4
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Research
1,478 papers~6 min read
Article
10 sectionsContents
- Medical uses
- Contraindications
- Side effects
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Chemistry
- History
- References
- External links
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| tradename = Corgard, others | Drugs.com = | MedlinePlus = a682666 | DailyMedID = Nadolol | pregnancy_AU = | pregnancy_US = C | pregnancy_category = | legal_UK = POM | legal_US = Rx-only | legal_status = | routes_of_administration = Oral | class = Beta blocker; β-Adrenergic receptor antagonist; Non-selective β1- and β2-adrenergic receptor antagonist | ATC_prefix = C07 | ATC_suffix = AA12