narcolessia

Key facts

Medical condition (new).name

Narcolepsy

Medical condition (new).image

1R02 crystallography.png

Medical condition (new).caption

The concentration of orexin-A neuropeptides in the cerebrospinal fluid of narcoleptic individuals is usually very low

Medical condition (new).field

Sleep medicine, neurology

Medical condition (new).symptoms

Excessive daytime sleepiness, involuntary sleep episodes, sudden loss of muscle strength, hallucinations

Medical condition (new).complications

Motor vehicle collisions, falls

Medical condition (new).onset

Adolescence

Medical condition (new).duration

Lifelong

Medical condition (new).causes

Orexin deficiency

Medical condition (new).risks

Family history, brain injury

Medical condition (new).diagnosis

Based on the symptoms and sleep studies

Medical condition (new).differential

Sleep apnea, major depressive disorder, anemia, heart failure, drinking alcohol, idiopathic hypersomnia, sleep deprivation, Kleine-Levin syndrome

Medical condition (new).treatment

Medication, regular short naps, sleep hygiene

Medical condition (new).medication

Stimulants (modafinil, pitolisant, solriamfetol, methylphenidate, amphetamine), sodium oxybate, mixed oxybate salts, serotonin reuptake inhibitors

Medical condition (new).frequency

0.2 to 600 per 100,000

via Wikipedia infobox

• Narcolepsy.ReviewThe New England journal of medicine · 2015Scammell TEDOI: 10.1056/NEJMra1500587
• Narcolepsy and Idiopathic Hypersomnia.ReviewSleep medicine clinics · 2023Blattner M, Maski KDOI: 10.1016/j.jsmc.2023.01.003
• Narcolepsy: Beyond the Classic Pentad.ReviewCNS drugs · 2025Morse AM, Kim SY, Harris S et al.DOI: 10.1007/s40263-024-01141-9
• Narcolepsy.ReviewNature reviews. Disease primers · 2017Kornum BR, Knudsen S, Ollila HM et al.DOI: 10.1038/nrdp.2016.100
• Narcolepsy.ReviewSouthern medical journal · 2003Feldman NTDOI: 10.1097/01.smj.0000056655.15660.42
• Narcolepsy.ReviewThe Nursing clinics of North America · 2002Rogers AE, Dreher HMDOI: 10.1016/s0029-6465(02)00035-x
• Narcolepsy.ReviewThe New England journal of medicine · 1973Zarcone VDOI: 10.1056/NEJM197305312882205
• Narcolepsy type 1: what have we learned from genetics?ReviewSleep · 2020Ollila HMDOI: 10.1093/sleep/zsaa099

via PubMed

Wikidata facts

Subclass of

excessive daytime sleepiness

Image

1R02 crystallography.png

via Wikidata · CC0