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nephrocalcinosis

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Also known as Hypercalcemic nephropathy

thumb|Kidney showing circumscribed calcium deposits together with a partial stag horn calculus. Nephrocalcinosis, once known as '''Albright's calcinosis''' after Fuller Albright, is a term originally used to describe the deposition of poorly soluble calcium salts in the renal parenchyma due to hyperparathyroidism. The term nephrocalcinosis is used to describe the deposition of both calcium oxalate and calcium phosphate. It may cause acute kidney injury. It is now more commonly used to describe diffuse, fine, renal parenchymal calcification in radiology. It is caused by multiple different condi

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Wikidata facts

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NCI Thesaurus ID
C84918
ICD-9-CM
275.49
Commons category
Nephrocalcinosis
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~9 min read

Article

12 sections
Contents
  • Signs and symptoms
  • Cause
  • Medullary nephrocalcinosis
  • Hypercalciuria without hypercalcaemia
  • Mechanism
  • Diagnosis
  • Stages of nephrocalcinosis
  • Treatment
  • Prognosis
  • Recent research
  • References
  • External links

thumb|Kidney showing circumscribed calcium deposits together with a partial stag horn calculus. Nephrocalcinosis, once known as '''Albright's calcinosis after Fuller Albright, is a term originally used to describe the deposition of poorly soluble calcium salts in the renal parenchyma due to hyperparathyroidism. The term nephrocalcinosis is used to describe the deposition of both calcium oxalate and calcium phosphate. It may cause acute kidney injury. It is now more commonly used to describe diffuse, fine, renal parenchymal calcification in radiology. It is caused by multiple different conditions and is determined by progressive kidney dysfunction. These outlines eventually come together to form a dense mass. During its early stages, nephrocalcinosis is visible on x-ray, and appears as a fine granular mottling over the renal outlines. It is most commonly seen as an incidental finding with medullary sponge kidney on an abdominal x-ray. It may be severe enough to cause (as well as be caused by) renal tubular acidosis or even end stage kidney disease, due to disruption of the kidney tissue by the deposited calcium salts.

==Signs and symptoms== Though this condition is usually asymptomatic, if symptoms are present they are usually related to the causative process, (e.g. hypercalcemia). Some of the symptoms that can happen are blood in the urine, fever and chills, nausea and vomiting, severe pain in the belly area, flanks of the back, groin, or testicles.

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