nicorandil
Also known as Ikorel®, SG-75, N-(2-hydroxyethyl)nicotinamide nitrate, 2-nicotinamidoethyl nitrate, SG 75, 2-Nicotinamidoethyl nitrate, Nicorandilum, N-(2-Hydroxyethyl)nicotinamide nitrate
Nicorandil is a vasodilator drug used to treat angina, which is chest pain that results from episodes of transient myocardial ischemia. Angina can be caused by diseases such as atherosclerosis, coronary artery disease, and aortic stenosis.
Research
1,985 papers- Nicorandil alleviates cardiac microvascular ferroptosis in diabetic cardiomyopathy: Role of the mitochondria-localized AMPK-Parkin-ACSL4 signaling pathway.Pharmacological research · 2024
- Nicorandil: animal pharmacology.The American journal of cardiology · 1989
- Nicorandil-associated ulcerations.European journal of gastroenterology & hepatology · 2007
- Nicorandil - an Effective Multitarget Drug for Cardioprotection?Cardiovascular drugs and therapy · 2023
- Nicorandil: A drug with ongoing benefits and different mechanisms in various diseased conditions.Indian journal of pharmacology · 2019
via PubMed
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Article
7 sectionsContents
- Side effects
- Mechanism of action
- Synthesis
- Names
- Brand names
- References
- Further reading
Nicorandil is a vasodilator drug used to treat angina, which is chest pain that results from episodes of transient myocardial ischemia. Angina can be caused by diseases such as atherosclerosis, coronary artery disease, and aortic stenosis.
It was patented in 1976 and approved for medical use in 1983.