nifuroxazide
Sign in to saveNifuroxazide (INN) is an oral nitrofuran antibiotic, patented since 1966 and used to treat colitis and diarrhea in humans and non-humans. It is sold under the brand names Ambatrol, Antinal, Bacifurane, Diafuryl (Turkey), Benol (Pakistan), Pérabacticel (France), Antinal, Diax (Egypt), Dearexin (Guatemala), Nifrozid, Ercefuryl (Romania, Czech Republic, Russia), Erfuzide (Thailand), Endiex (Slovakia), Enterofuryl (Bosnia and Herzegovina, Montenegro, North Macedonia, Russia), Pentofuryl (Germany), Nifuroksazyd Hasco, Nifuroksazyd Polpharma (Poland), Topron, Enterovid (Latin America), Eskapar (Mexi
Research
209 papers- Pharmacological updates of nifuroxazide: Promising preclinical effects and the underlying molecular mechanisms.European journal of pharmacology · 2023
- Nifuroxazide rescues the deleterious effects due to CHCHD10-associated MICOS defects in disease models.Brain : a journal of neurology · 2025
- Nifuroxazide Prevents Chikungunya Virus Infection Both In Vitro and In Vivo via Suppressing Viral Replication.Viruses · 2024
- Nifuroxazide induces apoptosis, inhibits cell migration and invasion in osteosarcoma.Investigational new drugs · 2019
- Nifuroxazide in combination with CpG ODN exerts greater efficacy against hepatocellular carcinoma.International immunopharmacology · 2022
via PubMed
Wikidata facts
- Subclass of
- heterocyclic compound
- Has part
- carbon
- Mass
- 275.054
Show 4 more facts
- chemical formula
- C₁₂H₉N₃O₅
- canonical SMILES
- C1=CC(=CC=C1C(=O)NN=CC2=CC=C(O2)[N+](=O)[O-])O
- isomeric SMILES
- C1=CC(=CC=C1C(=O)N/N=C/C2=CC=C(O2)[N+](=O)[O-])O
- Commons category
- Nifuroxazide
Sources (2)
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Encyclopedic overview
9 sectionsContents
- Medical uses
- Mechanism of action
- History
- Health claims
- Research directions
- STAT3 inhibition
- ALDH1 cancer stem cells
- USP21 inhibition
- References
Nifuroxazide (INN) is an oral nitrofuran antibiotic, patented since 1966 and used to treat colitis and diarrhea in humans and non-humans. It is sold under the brand names Ambatrol, Antinal, Bacifurane, Diafuryl (Turkey), Benol (Pakistan), Pérabacticel (France), Antinal, Diax (Egypt), Dearexin (Guatemala), Nifrozid, Ercefuryl (Romania, Czech Republic, Russia), Erfuzide (Thailand), Endiex (Slovakia), Enterofuryl (Bosnia and Herzegovina, Montenegro, North Macedonia, Russia), Pentofuryl (Germany), Nifuroksazyd Hasco, Nifuroksazyd Polpharma (Poland), Topron, Enterovid (Latin America), Eskapar (Mexico), Enterocolin, Terracolin (Bolivia), Apazid (Morocco), Nifroxid (Tunisia), Hufafural, Nifural (Indonesia), Nitronal (Georgia) and Septidiaryl. It is sold in capsule form and also as a suspension.
==Medical uses== Nifuroxazide have been found effective in infective diarrhea.
Excerpted from Wikipedia’s “nifuroxazide” article, available under the CC BY-SA 4.0 licence.
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