NLGN1

Also known as NL1, neuroligin 1

Neuroligin-1 is a protein that in humans is encoded by the NLGN1 gene.

Gene data

NLGN1

Name: neuroligin 1
Type: protein-coding
Position: 173,396,284–174,294,372 (+)
Aliases: NL1, NLG1
Ensembl: ENSG00000169760
RefSeq RNA: NM_001365923.2, NM_001365924.2, NM_001365925.2, NM_001365926.2, NM_001365927.2
RefSeq protein: NP_001352852.1, NP_001352853.1, NP_001352854.1, NP_001352855.1, NP_001352856.1

This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. [provided by RefSeq, Jul 2008].

Pathways

Cell adhesion molecules - Homo sapiens (human)Neuronal System Neuronal System Neurexins and neuroligins Neurexins and neuroligins Protein-protein interactions at synapses Protein-protein interactions at synapses Ectoderm Differentiation Serotonin and anxiety-related events Disruption of postsynaptic signaling by CNV

via MyGene.info

Gene · Ensembl

neuroligin 1

Symbol: NLGN1
Biotype: Protein coding
Organism: Homo sapiens
Location: 3:173,396,284-174,294,372
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts

HomoloGene ID: 56690
exact match: identifiers.org/ncbigene/22871
genomic end: 174294372
genomic start: 173114074
cytogenetic location: 3q26.31

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Neuroligin-1 is a protein that in humans is encoded by the NLGN1 gene.

This gene encodes a member of the neuroligin family of neuronal cell surface proteins. Neuroligin-1 acts as splice site-specific ligand for β-neurexins and has been shown to localize to the postsynaptic compartment at excitatory synapses and is involved in the formation and remodeling of central nervous system synapses.