Structure via PubChem · Public domain (PubChem)
o-phthalaldehyde
Sign in to saveAlso known as 1,2-Benzenedicarboxaldehyde, o-Phthaldehyde, Phthalaldialdehyde, o-Phthalicdicarboxaldehyde, Phthaldialdehyde, Phthalic aldehyde, OPA, Phthalic dialdehyde
Phthalaldehyde (sometimes also '''o-phthalaldehyde or ortho-phthalaldehyde, OPA''') is the chemical compound with the formula C6H4(CHO)2. It is one of three isomers of benzene dicarbaldehyde, related to phthalic acid. This pale yellow solid is a building block in the synthesis of heterocyclic compounds and a reagent in the analysis of amino acids. OPA dissolves in water solution at pH < 11.5. Its solutions degrade upon UV illumination and exposure to air.
In the Vinony graph
Vinony's link graph records 21 inbound references to o-phthalaldehyde, and connects out to disinfectant, International Standard Book Number and chemical compound.
Vinony files it under Benzaldehydes, Chembox having GHS data and ECHA InfoCard ID from Wikidata.
Vinony links it to 8 Wikipedia language editions.
Chemical data
- Formula
- C8H6O2
- Molecular weight
- 134.13 g/mol
- IUPAC name
- phthalaldehyde
- SMILES
- C1=CC=C(C(=C1)C=O)C=O
- InChIKey
- ZWLUXSQADUDCSB-UHFFFAOYSA-N
- XLogP
- 1.2
- Polar surface area
- 34.1 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
1,554 papers- Advances in the o-phthalaldehyde derivatizations. Comeback to the o-phthalaldehyde-ethanethiol reagent.Journal of chromatography. A · 2007
- O-phthalaldehyde assisted surface enhanced Raman spectroscopy selective determination of trace homocysteine in serum.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy · 2023
- O-Phthalaldehyde Derivatization for the Paper-Based Fluorometric Determination of Glutathione in Nutritional Supplements.Molecules (Basel, Switzerland) · 2024
- Determination of o-phthalaldehyde for dose verification of the clinical disinfectant by fluorescent sequential injection analysis.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2023
- Formation and instability of o-phthalaldehyde derivatives of amino acids.Analytical biochemistry · 1989
via PubMed
Wikidata facts
- Mass
- 134.037
Show 4 more facts
- chemical formula
- C₈H₆O₂
- canonical SMILES
- C1=CC=C(C(=C1)C=O)C=O
- subject has role
- disinfectant
- Commons category
- Phthalaldehyde
via Wikidata · CC0
~2 min read
Encyclopedic overview
7 sectionsContents
- Synthesis and reactions
- Biochemistry
- Disinfection
- Poly(phthalaldehyde)
- In winemaking
- Isomeric phthalaldehydes
- References
Phthalaldehyde (sometimes also '''o-phthalaldehyde or ortho-phthalaldehyde, OPA') is the chemical compound with the formula C6H4(CHO)2. It is one of three isomers of benzene dicarbaldehyde, related to phthalic acid. This pale yellow solid is a building block in the synthesis of heterocyclic compounds and a reagent in the analysis of amino acids. OPA dissolves in water solution at pH 6H4(CHO)(CH(OH)2) and C6H4(CH(OH))2O, respectively. Its reactions with nucleophiles often involves the reaction of both carbonyl groups.
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Excerpted from Wikipedia’s “o-phthalaldehyde” article, available under the CC BY-SA 4.0 licence.