o-phthalaldehyde
Sign in to saveAlso known as 1,2-Benzenedicarboxaldehyde, o-Phthaldehyde, Phthalaldialdehyde, o-Phthalicdicarboxaldehyde, Phthaldialdehyde, Phthalic aldehyde, OPA, Phthalic dialdehyde
Phthalaldehyde (sometimes also '''o-phthalaldehyde or ortho-phthalaldehyde, OPA''') is the chemical compound with the formula C6H4(CHO)2. It is one of three isomers of benzene dicarbaldehyde, related to phthalic acid. This pale yellow solid is a building block in the synthesis of heterocyclic compounds and a reagent in the analysis of amino acids. OPA dissolves in water solution at pH < 11.5. Its solutions degrade upon UV illumination and exposure to air.
Research
1,554 papers- Advances in the o-phthalaldehyde derivatizations. Comeback to the o-phthalaldehyde-ethanethiol reagent.Journal of chromatography. A · 2007
- O-phthalaldehyde assisted surface enhanced Raman spectroscopy selective determination of trace homocysteine in serum.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy · 2023
- O-Phthalaldehyde Derivatization for the Paper-Based Fluorometric Determination of Glutathione in Nutritional Supplements.Molecules (Basel, Switzerland) · 2024
- Determination of o-phthalaldehyde for dose verification of the clinical disinfectant by fluorescent sequential injection analysis.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2023
- Formation and instability of o-phthalaldehyde derivatives of amino acids.Analytical biochemistry · 1989
via PubMed
Wikidata facts
- Mass
- 134.037
Show 3 more facts
- chemical formula
- C₈H₆O₂
- canonical SMILES
- C1=CC=C(C(=C1)C=O)C=O
- Commons category
- Phthalaldehyde
via Wikidata · CC0
~2 min read
Article
7 sectionsContents
- Synthesis and reactions
- Biochemistry
- Disinfection
- Poly(phthalaldehyde)
- In winemaking
- Isomeric phthalaldehydes
- References
Phthalaldehyde (sometimes also '''o-phthalaldehyde or ortho-phthalaldehyde, OPA') is the chemical compound with the formula C6H4(CHO)2. It is one of three isomers of benzene dicarbaldehyde, related to phthalic acid. This pale yellow solid is a building block in the synthesis of heterocyclic compounds and a reagent in the analysis of amino acids. OPA dissolves in water solution at pH 6H4(CHO)(CH(OH)2) and C6H4(CH(OH))2O, respectively. Its reactions with nucleophiles often involves the reaction of both carbonyl groups.
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