orotic acid
Also known as orotate, 2,6-dioxo-3H-pyrimidine-4-carboxylic acid, Acide orotique, 1,2,3,6-Tetrahydro-2,6-dioxo-4-pyrimidecarboxylic acid, 2,6-Dihydroxypyrimidine-4-carboxylic acid, 6-Carboxyuracil, Oropur, 1,2,3,6-Tetrahydro-2,6-dioxo-4-Pyrimidinecarboxylic acid
chemical compound synthesized in the body via a mitochondrial enzyme
Key facts
- Other names
- uracil-6-carboxylic acid
- Ahfs drugs com
- International Drug Names
- Atc code
- none
- Cas number
- 65-86-1
- Drugbank
- DB02262
- Unii
- 61H4T033E5
- Kegg
- C00295
- Comptox dashboard u s environmental prot
- DTXSID0025814
- Echa infocard
- 100.000.563
- Formula
- C 5 H 4 N 2 O 4
- Molar mass
- 156.097 g·mol
- 3d model jsmol
- Interactive image
via Wikipedia infobox
Chemical data
~3 min read
Article
Orotic acid (/ɔːˈrɒtɪk/) is a pyrimidinedione and a carboxylic acid. Historically, it was believed to be part of the vitamin B complex and was called vitamin B13, but it is now known that it is not a vitamin.
The compound is synthesized in the body via a mitochondrial enzyme, dihydroorotate dehydrogenase or a cytoplasmic enzyme of pyrimidine synthesis pathway. It is sometimes used as a mineral carrier in some dietary supplements (to increase their bioavailability), most commonly for lithium orotate.