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oxazoline
EntityQ413567· pop 14· linked from 556 articles

Also known as 2-oxazoline

Oxazoline is a five-membered heterocyclic organic compound with the formula . It is the parent of a family of compounds called oxazolines (emphasis on plural), which contain non-hydrogenic substituents on carbon and/or nitrogen. Oxazolines are the unsaturated analogues of oxazolidines, and they are isomeric with isoxazolines, where the N and O are directly bonded. Two isomers of oxazoline are known, depending on the location of the double bond.

Wikidata facts

Mass
71.037
Show 3 more facts
chemical formula
C₃H₅NO
canonical SMILES
C1COC=N1
Commons category
2-Oxazoline
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~6 min read

Article

12 sections
Contents
  • Isomers
  • Synthesis
  • From carboxylic acids
  • From aldehydes
  • From nitriles
  • Applications
  • Ligands
  • Polymers
  • Analysis of fatty acids
  • Protecting groups
  • See also
  • References

Oxazoline is a five-membered heterocyclic organic compound with the formula . It is the parent of a family of compounds called oxazolines (emphasis on plural), which contain non-hydrogenic substituents on carbon and/or nitrogen. Oxazolines are the unsaturated analogues of oxazolidines, and they are isomeric with isoxazolines, where the N and O are directly bonded. Two isomers of oxazoline are known, depending on the location of the double bond.

Oxazoline itself has no applications however oxazolines have been widely investigated for potential applications. These applications include use as ligands in asymmetric catalysis, as protecting groups for carboxylic acids and increasingly as monomers for the production of polymers.

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