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оксикодон

File:Oxycodone.svg · Wikimedia Commons · See Wikimedia Commons

EntityQ407535· pop 49· linked from 1,646 articles

оксикодон

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Also known as dihydroxycodeinone, dihydrohydroxycodeinone, dihydro-14-hydroxycodeinone, 4,5alpha-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one, 4,5-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one, (-)-14-hydroxydihydrocodeinone, 4,5α-epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one, Oxycontin

обезболивающий препарат, полусинтетический опиоид, получаемый из тебаина

OverviewAI-generated

Oxycodone is a chemical compound with the formula C₁₈H₂₁NO₄. It was discovered in 1916. The substance has a mass of 315.147 and a weight of 315.4. Its IUPAC name is (4R,4aS,7aR,12bS)-4a-hydroxy-9-methoxy-3-methyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one.

The compound has a defined daily dose of 75. It carries a charge of 0, with an xlogp of 1.2 and a topological polar surface area of 59. Oxycodone features one hydrogen bond donor and five hydrogen bond acceptors. Stylized names for the substance include "oxyCODONE" and "OxyCONTIN".

Oxycodone is referenced by 1,646 other encyclopedia articles. A PubMed query for oxycodone returns a count of 6,111 entries.

Synthesized by Vinony from 21 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.

Key facts

Drug.C
18
Drug.H
21
Drug.N
1
Drug.O
4
Drug.verifiedrevid
464196835
Drug.image
Oxycodone.svg
Drug.image_class
skin-invert-image
Drug.width
183
Drug.image2
Oxycodone molecule ball.png
Drug.image_class2
bg-transparent
Drug.width2
225
Drug.tradename
Roxicodone, OxyContin, Endone, others
Drug.MedlinePlus
a682132
Drug.DailyMedID
Oxycodone
Drug.pregnancy_AU
C
Drug.dependency_liability
High
Drug.addiction_liability
High
Drug.routes_of_administration
By mouth, sublingual, intramuscular, intravenous, intranasal, subcutaneous, transdermal, rectal, epidural

via Wikipedia infobox

Chemical data

Formula
C18H21NO4
Molecular weight
315.4 g/mol
IUPAC name
(4R,4aS,7aR,12bS)-4a-hydroxy-9-methoxy-3-methyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-one
SMILES
CN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)OC)O4)O
InChIKey
BRUQQQPBMZOVGD-XFKAJCMBSA-N
XLogP
1.2
Polar surface area
59 Ų
H-bond donors
1
H-bond acceptors
5
Formal charge
0

via PubChem

Research

6,111 papers

via PubMed

Wikidata facts

Has part
carbon
Mass
315.147
Has use
medication
Show 13 more facts
Commons category
Oxycodone
chemical formula
C₁₈H₂₁NO₄
World Health Organisation international non-proprietary name
oxycodone
medical condition treated
injury
isomeric SMILES
CN1CC[C@]23[C@@H]4C(=O)CC[C@]2([C@H]1CC5=C3C(=C(C=C5)OC)O4)O
canonical SMILES
CN1CCC23C4C(=O)CCC2(C1CC5=C3C(=C(C=C5)OC)O4)O
subject has role
essential medicine
time of discovery or invention
1916-00-00
found in taxon
Papaver somniferum
stylized name
OxyCONTIN
defined daily dose
30
legal status (medicine)
boxed warning
significant drug interaction
primidone
Sources (7)

via Wikidata · CC0

Article · Русский

Оксикодон (перкоцет, перкосет) — обезболивающий препарат, полусинтетический опиоид, получаемый из тебаина. Разработан в 1916 году в Германии. Являлся одним из нескольких новых полусинтетических опиоидов, созданных в попытке улучшить существующие опиоиды: морфин, диацетилморфин (героин) и кодеин. Оксикодон обычно выписывается для облегчения умеренной или сильной боли.

Abstract from DBpedia / Wikipedia · CC BY-SA

Gallery (20)

оксикодон · Vinony