parathion
Sign in to saveAlso known as O,O-diethyl-O(p-nitrophenyl) phosphorothioate, diethyl parathion, ethyl parathion, parathion-ethyl, O,O-diethyl O-(p-nitrophenyl) thiophosphate, diethyl p-nitrophenyl thiophosphate, phosphorothioic acid, O,O-diethyl O-(4-nitrophenyl) ester, O,O-diethyl O-(4-nitrophenyl) thiophosphate
Parathion, also called parathion-ethyl or diethyl parathion, is an organophosphate insecticide and acaricide. It was originally developed by IG Farben in the 1940s. It is highly toxic to non-target organisms, including humans, so its use has been banned or restricted in most countries. In response to safety concerns, the less toxic but still dangerous analogue parathion methyl was later developed.
Research
4,465 papers- Parathion poisoning.British medical journal · 1950
- Parathion: residues in soil and water.Residue reviews · 1977
- Parathion.IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans · 1983
- Parathion poisoning.American practitioner and digest of treatment · 1951
- [p-Nitrophenol].Nihon rinsho. Japanese journal of clinical medicine · 2004
via PubMed
Wikidata facts
- Mass
- 291.033
Show 12 more facts
- immediately dangerous to life or health
- 10
- melting point
- 43
- Commons category
- Parathion
- boiling point
- 707
- chemical formula
- C₁₀H₁₄NO₅PS
- NIOSH Pocket Guide ID
- 0479
- density
- 1.27
- vapor pressure
- 0.00004
- flash point
- 392
- solubility
- 0.001
- time-weighted average exposure limit
- 0.1
- canonical SMILES
- CCOP(=S)(OCC)OC1=CC=C(C=C1)[N+](=O)[O-]
Sources (6)
via Wikidata · CC0
~6 min read
Article
12 sectionsContents
- History
- Handling properties
- Industrial synthesis
- Applications
- Insecticidal activity
- Degradation
- Safety
- Protection against poisoning
- Use in suicides
- See also
- References
- External links
Parathion, also called parathion-ethyl or diethyl parathion, is an organophosphate insecticide and acaricide. It was originally developed by IG Farben in the 1940s. It is highly toxic to non-target organisms, including humans, so its use has been banned or restricted in most countries. In response to safety concerns, the less toxic but still dangerous analogue parathion methyl was later developed.
==History== thumb|Bottle with E605 Parathion was developed by Gerhard Schrader for the German trust IG Farben in the 1940s. After World War II and the collapse of IG Farben due to the war crime trials, the Western allies seized the patent, and parathion was marketed worldwide by different companies and under different brand names. The most common German brand was E605 (banned in Germany after 2002); this was not a food-additive "E number" as used in the EU today. "E" stands for Entwicklungsnummer (German for "development number"). It is an irreversible acetylcholinesterase inhibitor.