arsphenamine
Also known as Salvarsan, arsenphenolamine hydrochloride, 4,4'-arsenobis(2-aminophenol) dihydrochloride, 3,3'-diamino-4,4'-dihydroxyarsenobenzene dihydrochloride, Ehrlich 606, 4,4'-(diarsene-1,2-diyl)bis(2-aminophenol) dihydrochloride, 4,4'-(1,2-diarsenediyl)bis(2-aminophenol) dihydrochloride
thumb|right|300px|The structure of arsphenamine has been proposed to be akin to azobenzene (A). Salvarsan is now assumed to be a mixture of the trimer (B) and the pentamer (C).
Chemical data
- Formula
- C12H14As2Cl2N2O2
- Molecular weight
- 439 g/mol
- IUPAC name
- [5-(3-azaniumyl-4-hydroxyphenyl)arsanylidenearsanyl-2-hydroxyphenyl]azanium dichloride
- SMILES
- C1=CC(=C(C=C1[As]=[As]C2=CC(=C(C=C2)O)[NH3+])[NH3+])O.[Cl-].[Cl-]
- InChIKey
- VLAXZGHHBIJLAD-UHFFFAOYSA-N
- Polar surface area
- 95.7 Ų
- H-bond donors
- 4
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Research
543 papersArticle
4 sectionsContents
- History
- Structure
- See also
- References
thumb|right|300px|The structure of arsphenamine has been proposed to be akin to azobenzene (A). Salvarsan is now assumed to be a mixture of the trimer (B) and the pentamer (C).
Arsphenamine, also known as Salvarsan or compound 606, is an antibiotic drug that was introduced at the beginning of the 1910s as the first effective treatment for the deadly infectious diseases syphilis, relapsing fever, and African trypanosomiasis. This organoarsenic compound was the first modern antimicrobial agent.