paratope
Sign in to saveAlso known as antigen-binding site
thumb| An antibody with a circled region depicting where the paratope is found. 1. Fragment antigen-binding|Antigen-binding fragment (Fab) 2. Antibody crystallizable region (Fc) 3. Heavy chains 4. Light chains 5. Variable region of the antibody. The paratope is the key-shaped section that makes direct contact with the [[antigen. 6. Hinge regions ]]
In the Vinony graph
Within Vinony's link graph, paratope is referenced by 107 other articles, and connects out to International Standard Book Number, allergy and digital object identifier.
It is catalogued under the topic Immune system.
Its subject is documented across 15 Wikipedia language editions.
Wikidata facts
- Subclass of
- binding site
Show 1 more fact
- physically interacts with
- epitope
Sources (2)
via Wikidata · CC0
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Encyclopedic overview
2 sectionsContents
- Design of paratopes between species
- References
thumb| An antibody with a circled region depicting where the paratope is found. 1. Fragment antigen-binding|Antigen-binding fragment (Fab) 2. Antibody crystallizable region (Fc) 3. Heavy chains 4. Light chains 5. Variable region of the antibody. The paratope is the key-shaped section that makes direct contact with the [[antigen. 6. Hinge regions ]]
In immunology, a paratope, also known as an antigen-binding site, is the part of an antibody which recognizes and binds to an antigen. It is a small region at the tip of the antibody's antigen-binding fragment and contains parts of the antibody's heavy and light chains. Each paratope is made up of six complementarity-determining regions - three from each of the light and heavy chains - that extend from a fold of anti-parallel beta sheets. Each arm of the Y-shaped antibody has an identical paratope at the end.
Excerpted from Wikipedia’s “paratope” article, available under the CC BY-SA 4.0 licence.