PDCD10

Name

programmed cell death 10

Type

protein-coding

Aliases

CCM3, TFAR15

This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

programmed cell death 10

Symbol

PDCD10

Biotype

Protein coding

Organism

Homo sapiens

Location

3:167,677,517-167,735,039

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Image

Protein PDCD10 PDB 3AJM.png

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