Pentraxins
Sign in to saveAlso known as pentraxin, pentaxin, pentaxins
Pentraxins (PTX), also known as pentaxins, are an evolutionary conserved family of proteins characterised by containing a pentraxin protein domain. Proteins of the pentraxin family are involved in acute immunological responses. They are a class of pattern recognition receptors (PRRs). They are a superfamily of multifunctional conserved proteins, some of which are components of the humoral arm of innate immunity and behave as functional ancestors of antibodies (Abs). They are known as classical acute phase proteins (APP), known for over a century.
Research
63,172 papers- Pentraxins in Complement Activation and Regulation.Frontiers in immunology · 2018
- Regulation of the Complement System by Pentraxins.Frontiers in immunology · 2019
- Neuronal pentraxins as biomarkers of synaptic activity: from physiological functions to pathological changes in neurodegeneration.Journal of neural transmission (Vienna, Austria : 1996) · 2022
- Pentraxins in humoral innate immunity.Advances in experimental medicine and biology · 2012
- Pattern recognition by pentraxins.Advances in experimental medicine and biology · 2009
via PubMed
~4 min read
Article
9 sectionsContents
- Structure
- Family members
- C-reactive protein
- Pentraxin 3
- Serum amyloid P component
- Hamster female protein
- Nervous system
- Human
- References
Pentraxins (PTX), also known as pentaxins, are an evolutionary conserved family of proteins characterised by containing a pentraxin protein domain. Proteins of the pentraxin family are involved in acute immunological responses. They are a class of pattern recognition receptors (PRRs). They are a superfamily of multifunctional conserved proteins, some of which are components of the humoral arm of innate immunity and behave as functional ancestors of antibodies (Abs). They are known as classical acute phase proteins (APP), known for over a century.
== Structure ==