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peramivir

Structure via PubChem · Public domain (PubChem)

EntityQ412734· pop 15· linked from 212 articles

Also known as BCX-1812, 3-(1'-acetylamino-2'-ethyl)butyl-4-((aminoimino)methyl)amino-2-hydroxycyclopentane-1-carboxylic acid, BCX 1812, BCX1812, RWJ 270201, RWJ270201, RWJ-270201, peramivir anhydrous

thumb|Exterior of Rapiacta I.V. Bag 300mg (Generic name: Peramivir hydrate). An anti-influenza virus drug administered by intravenous infusion in Japan.

In the Vinony graph

Within Vinony's link graph, peramivir is referenced by 212 other articles, and connects out to influenza, 1918–1920 flu pandemic and 2009 swine flu pandemic.

It is catalogued under topics including Acetamides, Chemical articles with multiple CAS registry numbers and Chemicals using indexlabels.

Its subject is documented across 14 Wikipedia language editions.

Chemical data

Formula
C15H28N4O4
Molecular weight
328.41 g/mol
IUPAC name
(1S,2S,3S,4R)-3-[(1S)-1-acetamido-2-ethylbutyl]-4-(diaminomethylideneamino)-2-hydroxycyclopentane-1-carboxylic acid
SMILES
CCC(CC)[C@@H]([C@H]1[C@@H](C[C@@H]([C@H]1O)C(=O)O)N=C(N)N)NC(=O)C
InChIKey
XRQDFNLINLXZLB-CKIKVBCHSA-N
XLogP
0
Polar surface area
151 Ų
H-bond donors
5
H-bond acceptors
5
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Approved
Molecule type
Small molecule
First approval
2014
Admin. routes
parenteral
Indications
viral disease, influenza

via ChEMBL · EBI

Wikidata facts

Mass
328.211
Has use
medication
Show 6 more facts
chemical formula
C₁₅H₂₈N₄O₄
canonical SMILES
CCC(CC)C(C1C(CC(C1O)C(=O)O)N=C(N)N)NC(=O)C
Commons category
Peramivir
isomeric SMILES
CCC(CC)[C@H](NC(C)=O)[C@@H]1[C@H](O)[C@H](C[C@H]1NC(N)=N)C(O)=O
medical condition treated
influenza
subject has role
antiviral drug
Sources (4)

via Wikidata · CC0

~4 min read

Encyclopedic overview

3 sections
Contents
  • History
  • References
  • External links

thumb|Exterior of Rapiacta I.V. Bag 300mg (Generic name: Peramivir hydrate). An anti-influenza virus drug administered by intravenous infusion in Japan.

Peramivir (trade name Rapivab) is an antiviral drug developed by BioCryst Pharmaceuticals for the treatment of influenza. Peramivir is a neuraminidase inhibitor, acting as a transition-state analogue inhibitor of influenza neuraminidase and thereby preventing new viruses from emerging from infected cells. It is approved for intravenous administration.

Excerpted from Wikipedia’s “peramivir” article, available under the CC BY-SA 4.0 licence.

Gallery (2)

Connections

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