peroxisome

300px|right|thumb|Basic structure of a peroxisome thumb|300px|Distribution of peroxisomes (white) in HEK 293 cells during [[mitosis]] alt=Peroxisome in rat neonatal cardiomyocyte staining The SelectFX Alexa Fluor 488 Peroxisome Labeling Kit directed against peroxisomal membrane protein 70 (PMP 70)|thumb|Peroxisome in rat neonatal cardiomyocyte

AI overview

A peroxisome is a small, membrane-bound compartment inside cells that contains enzymes and helps break down fatty acids and other molecules. These organelles are important for protecting cells from harmful substances called peroxides, which they break down into water and oxygen.

AI-generated from the Wikipedia summary — may contain errors.

Research

56,185 papers

Peroxisome: Metabolic Functions and Biogenesis.ReviewAdvances in experimental medicine and biology · 2020Okumoto K, Tamura S, Honsho M et al.DOI: 10.1007/978-3-030-60204-8_1
The peroxisome: an up-and-coming organelle in immunometabolism.ReviewTrends in cell biology · 2023Di Cara F, Savary S, Kovacs WJ et al.DOI: 10.1016/j.tcb.2022.06.001
The peroxisome: an update on mysteries 3.0.ReviewHistochemistry and cell biology · 2024Kumar R, Islinger M, Worthy H et al.DOI: 10.1007/s00418-023-02259-5
Peroxisome Metabolism in Cancer.ReviewCells · 2020Kim JADOI: 10.3390/cells9071692
Peroxisome Biogenesis Disorders.ReviewAdvances in experimental medicine and biology · 2020Honsho M, Okumoto K, Tamura S et al.DOI: 10.1007/978-3-030-60204-8_4
Glutathione and peroxisome redox homeostasis.ReviewRedox biology · 2023Ferreira MJ, Rodrigues TA, Pedrosa AG et al.DOI: 10.1016/j.redox.2023.102917
Peroxisome biogenesis, membrane contact sites, and quality control.ReviewEMBO reports · 2019Farré JC, Mahalingam SS, Proietto M et al.DOI: 10.15252/embr.201846864
Peroxisome biogenesis.ReviewAnnual review of cell and developmental biology · 2001Purdue PE, Lazarow PBDOI: 10.1146/annurev.cellbio.17.1.701

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Wikidata facts

Image: Število peroksisomov pri kvasovki H. polymorpha.jpg

Show 2 more facts

exact match: purl.obolibrary.org/obo/GO_0005777
Commons category: Peroxisomes

Sources (4)

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~13 min read

Article

13 sections

Contents

History
Structure
Metabolic functions
Peroxisome assembly
Peroxisome interaction and communication
Associated medical conditions
Genes
Evolutionary origins
Other related organelles
See also
References
Further reading
External links

A peroxisome () is a membrane-bound organelle, a type of microbody, found in the cytoplasm of virtually all eukaryotic cells. Peroxisomes are oxidative organelles. Frequently, molecular oxygen serves as a co-substrate, from which hydrogen peroxide (H2O2) is then formed. Peroxisomes owe their name to hydrogen peroxide-generating and scavenging activities. They perform key roles in lipid metabolism and the reduction of reactive oxygen species.