Phosphoglycerate mutase
Sign in to saveAlso known as PGA mutase, monophosphoglyceromutase, monophosphoglycerate mutase, PGAM, phosphoglycerate phosphomutase, D-phosphoglycerate 2,3-phosphomutase, PGM, phosphoglyceromutase
class of enzymes
In the Vinony graph
Vinony's link graph records 190 inbound references to Phosphoglycerate mutase, and connects out to (RS)-3-phosphoglyceric acid, 2-phosphoglyceric acid and DL-glyceric acid 1,3-biphosphate.
Vinony files it under EC 5.4.2, Genes on human chromosome 10 and Genes on human chromosome 7.
Vinony links it to 17 Wikipedia language editions.
Research
1,270 papers- Thermal proteome profiling reveals fructose-1,6-bisphosphate as a phosphate donor to activate phosphoglycerate mutase 1.Nature communications · 2024
- Phosphoglycerate mutase 5 initiates inflammation in acute kidney injury by triggering mitochondrial DNA release by dephosphorylating the pro-apoptotic protein Bax.Kidney international · 2023
- Phosphoglycerate mutase 1-mediated dephosphorylation and degradation of Dusp1 disrupt mitochondrial quality control and exacerbate endotoxemia-induced myocardial dysfunction.Theranostics · 2024
- Phosphoglycerate mutase 1 in cancer: A promising target for diagnosis and therapy.IUBMB life · 2019
- A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer.Cell metabolism · 2019
via PubMed
Wikidata facts
- Image
- Homodimer B-type PGM.png
Show 2 more facts
- Commons category
- Phosphoglycerate mutase
- EC enzyme number
- 5.4.2.11
via Wikidata · CC0
Connections
(RS)-3-phosphoglyceric acid
Entity
2-phosphoglyceric acid
Entity
DL-glyceric acid 1,3-biphosphate
Entity
2,3-diphosphoglyceric acid
Entity
protein superfamily
Entity
enzyme
Entity
metabolism
Entity
ion
Entity
glucose
Entity
digital object identifier
Entity
glycerol
Entity
phosphates
Entity
glycolytic process
Entity
L-alanine
Entity
DL-lactic acid
Entity
Q180686
Entity
tricarboxylic acid cycle
Entity
L-aspartic acid
Entity
bibcode
Entity
L-histidine
Entity