PIK3CG
Sign in to saveAlso known as PI3CG, PI3K, PI3Kgamma, PIK3, p110gamma, p120-PI3K, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma, IMD97
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform is an enzyme that in humans is encoded by the PIK3CG gene.
In the Vinony graph
Within Vinony's link graph, PIK3CG is referenced by 14 other articles, and connects out to PubMed, human chromosome 7 and Ensembl genome database project.
It sits within the topics Cell signaling, EC 2.7.1 and Genes on human chromosome 7.
Its subject is documented across 5 Wikipedia language editions.
Gene data
PIK3CG- Name
- phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
- Type
- protein-coding
- Position
- 106,865,278–106,908,980 (+)
- Aliases
- IMD97, PI3CG, PI3K, PI3Kgamma, PIK3, p110gamma, p120-PI3K
- Ensembl
- ENSG00000105851
- RefSeq RNA
- NM_001282426.2, NM_001282427.2, NM_002649.3, XM_005250443.4, XM_011516316.2
- RefSeq protein
- NP_001269355.1, NP_001269356.1, NP_002640.2, XP_005250500.1, XP_011514618.1
Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I catalytic subunit of PI3K. Like other class I catalytic subunits (p110-alpha p110-beta, and p110-delta), the encoded protein binds a p85 regulatory subunit to form PI3K. This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2015].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
- Symbol
- PIK3CG
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:106,865,278-106,908,980
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 68269
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5294
- genomic end
- 106908980
- genomic start
- 106505723
- chromosome
- human chromosome 7
- cytogenetic location
- 7q22.3
- expressed in
- visceral pleura
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Interactions
- See also
- References
- Further reading
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform is an enzyme that in humans is encoded by the PIK3CG gene.
== Function ==
Excerpted from Wikipedia’s “PIK3CG” article, available under the CC BY-SA 4.0 licence.