pirlindole
Sign in to saveAlso known as Pyrazidol ®
Pirlindole, sold under the brand names Lifril and Pyrazidol, is mainly a reversible inhibitor of monoamine oxidase A (RIMA) and secondly a serotonin–norepinephrine reuptake inhibitor (SNRI) which was developed and is used in Russia as an antidepressant. It is structurally and pharmacologically related to metralindole.
Research
124 papers- Pirlindole in the treatment of depression: a meta-analysis.Clinical drug investigation · 2011
- Pirlindole in the treatment of depression and fibromyalgia syndrome.Clinical drug investigation · 2011
- Pirlindole: a selective reversible inhibitor of monoamine oxidase A. A review of its preclinical properties.Pharmacological research · 1997
- Effects of the antidepressant pirlindole and its dehydro-derivative on the activity of monoamine oxidase-A and on GABAA receptors.Neurochemical research · 1996
- The influence of the antidepressant pirlindole and its dehydro-derivative on the activity of monoamine oxidase A and GABAA receptor binding.Journal of neural transmission. Supplementum · 1998
via PubMed
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Encyclopedic overview
3 sectionsContents
- Synthesis
- See also
- References
Pirlindole, sold under the brand names Lifril and Pyrazidol, is mainly a reversible inhibitor of monoamine oxidase A (RIMA) and secondly a serotonin–norepinephrine reuptake inhibitor (SNRI) which was developed and is used in Russia as an antidepressant. It is structurally and pharmacologically related to metralindole.
==Synthesis== thumb|400px|center|class=skin-invert-image|Synthesis: Patents: Sino: Enantiomers:
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