plasmalogens
Sign in to saveAlso known as plasmenyl-phospholipid, plasmalogen
thumb|250px|Example of an ethanolamine plasmalogen with the characteristic vinyl ether linkage at the sn-1 position and an ester linkage at the sn-2 position
Research
3,036 papers- Plasmalogens: A potential therapeutic target for neurodegenerative and cardiometabolic disease.Progress in lipid research · 2019
- Plasmalogens and platelet-activating factor roles in chronic inflammatory diseases.BioFactors (Oxford, England) · 2022
- Interplay between cardiolipin and plasmalogens in Barth syndrome.Journal of inherited metabolic disease · 2022
- Plasmalogens, platelet-activating factor and beyond - Ether lipids in signaling and neurodegeneration.Neurobiology of disease · 2020
- Plasmalogens the neglected regulatory and scavenging lipid species.Chemistry and physics of lipids · 2011
via PubMed
~9 min read
Article
14 sectionsContents
- Structure
- Functions
- History
- Biosynthesis
- Pathology
- During inflammation
- Possible disease links
- Evolution
- In bacteria
- Among eukaryotes
- Among primates
- See also
- References
- External links
thumb|250px|Example of an ethanolamine plasmalogen with the characteristic vinyl ether linkage at the sn-1 position and an ester linkage at the sn-2 position
Plasmalogens are a class of glycerophospholipid with a plasmenyl group linked to a lipid at the sn-1 position of the glycerol backbone. Plasmalogens are found in multiple domains of life, including mammals, invertebrates, protozoa, and anaerobic bacteria. They are commonly found in cell membranes in the nervous, immune, and cardiovascular systems. In humans, lower levels of plasmalogens are studied in relation to some diseases. Plasmalogens are also associated with adaptations to extreme environments in non-human organisms.