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پروکائین

File:Procaine.svg · Wikimedia Commons · See Wikimedia Commons

EntityQ423741· pop 39· linked from 508 articles

پروکائین

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Also known as Novocain®, beta-(diethylamino)ethyl 4-aminobenzoate, beta-(diethylamino)ethyl p-aminobenzoate, Vitamin H3, 2-Diethylaminoethyl p-aminobenzoate, p-Aminobenzoic acid 2-diethylaminoethyl ester, novocaine, 4-aminobenzoic acid 2-diethylaminoethyl ester

Procaine is a local anesthetic drug of the amino ester group. It is most commonly used in dental procedures to numb the area around a tooth and is also used to reduce the pain of intramuscular injection of penicillin. Owing to the ubiquity of the trade name Novocain (without the "e" in the original German patent) or Novocaine (with the "e" in the US patent), in some regions, procaine is referred to generically as novocaine. It acts mainly as a sodium channel blocker. Today, it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion-enhancing, and mood-e

OverviewAI-generated

Procaine is a chemical compound with the formula C₁₃H₂₀N₂O₂. Its IUPAC name is 2-(diethylamino)ethyl 4-aminobenzoate. The substance has a mass of 236.152 and a weight of 236.31. It possesses a charge of 0, an xlogp of 1.9, and a topological polar surface area of 55.6. The molecule contains one hydrogen bond donor and four hydrogen bond acceptors.

In scientific literature, procaine is the subject of 13,764 PubMed entries. The compound is also referenced by 508 other encyclopedia articles.

Synthesized by Vinony from 17 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.

Chemical data

Formula
C13H20N2O2
Molecular weight
236.31 g/mol
IUPAC name
2-(diethylamino)ethyl 4-aminobenzoate
SMILES
CCN(CC)CCOC(=O)C1=CC=C(C=C1)N
InChIKey
MFDFERRIHVXMIY-UHFFFAOYSA-N
XLogP
1.9
Polar surface area
55.6 Ų
H-bond donors
1
H-bond acceptors
4
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Approved
Molecule type
Small molecule
First approval
1954
Admin. routes
parenteral
Indications
osteomyelitis, hemorrhoid

via ChEMBL · EBI

Research

13,764 papers

via PubMed

Wikidata facts

Has part
oxygen
Mass
236.152
Has use
medication
Show 8 more facts
described by source
Armenian Soviet Encyclopedia
medical condition treated
pain
chemical formula
C₁₃H₂₀N₂O₂
Commons category
Procaine
canonical SMILES
CCN(CC)CCOC(=O)C1=CC=C(C=C1)N
World Health Organisation international non-proprietary name
procaine
subject has role
local anesthetic
discoverer or inventor
Heinrich Braun
Sources (4)

via Wikidata · CC0

Gallery (9)