propagermanium
Sign in to saveAlso known as Proxigermanium, 2-carboxyethylgermasesquioxane, 3,3'-(1,3-dioxo-1,3-digermoxanediyl)dipropionic acid, carboxyethylgermanium sesquioxide
Propagermanium (INN), also known by a variety of other names including bis(2-carboxyethylgermanium) sesquioxide and 2-carboxyethylgermasesquioxane, is an organometallic compound of germanium that is sold as an alternative medicine. It is a polymeric compound with the formula ((HOOCCH2CH2Ge)2O3)n.
Research
118 papers- Propagermanium: a nonspecific immune modulator for chronic hepatitis B.Journal of gastroenterology · 2003
- Propagermanium as a Novel Therapeutic Approach for the Treatment of Endothelial Dysfunction in Type 2 Diabetes.International journal of molecular sciences · 2024
- Potentials of C-C motif chemokine 2-C-C chemokine receptor type 2 blockers including propagermanium as anticancer agents.Cancer science · 2019
- Propagermanium, a CCR2 inhibitor, attenuates cerebral ischemia/reperfusion injury through inhibiting inflammatory response induced by microglia.Neurochemistry international · 2019
- Antagonizing CCR2 With Propagermanium Leads to Altered Distribution of Macrophage Subsets and Favorable Tissue Remodeling After Myocardial Infarction in Mice.Cardiovascular therapeutics · 2025
via PubMed
Wikidata facts
- Mass
- 341.8850082599999
Show 2 more facts
- chemical formula
- C₆H₁₀Ge₂O₇
- canonical SMILES
- C(C[Ge](=O)O[Ge](=O)CCC(=O)O)C(=O)O
Sources (2)
via Wikidata · CC0
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Article
1 sectionsContents
- References
Propagermanium (INN), also known by a variety of other names including bis(2-carboxyethylgermanium) sesquioxide and 2-carboxyethylgermasesquioxane, is an organometallic compound of germanium that is sold as an alternative medicine. It is a polymeric compound with the formula ((HOOCCH2CH2Ge)2O3)n.
The compound was first synthesized in 1967 at the Asai Germanium Research Institute in Japan. It is a water-soluble organogermanium compound used as raw material in nutritional supplements. The compound displays low toxicity in studies with rats.