Structure via PubChem · Public domain (PubChem)
propagermanium
Sign in to saveAlso known as Proxigermanium, 2-carboxyethylgermasesquioxane, 3,3'-(1,3-dioxo-1,3-digermoxanediyl)dipropionic acid, carboxyethylgermanium sesquioxide
Propagermanium (INN), also known by a variety of other names including bis(2-carboxyethylgermanium) sesquioxide and 2-carboxyethylgermasesquioxane, is an organometallic compound of germanium that is sold as an alternative medicine. It is a polymeric compound with the formula ((HOOCCH2CH2Ge)2O3)n.
In the Vinony graph
Vinony's link graph records 3 inbound references to propagermanium, and connects out to Japan, International Standard Book Number and germanium.
It is catalogued under topics including Chembox having GHS data, Chembox image size set and ECHA InfoCard ID from Wikidata.
Vinony links it to 10 Wikipedia language editions.
Chemical data
- Formula
- C6H10Ge2O7
- Molecular weight
- 339.4 g/mol
- IUPAC name
- 3-[[2-carboxyethyl(oxo)germyl]oxy-oxogermyl]propanoic acid
- SMILES
- C(C[Ge](=O)O[Ge](=O)CCC(=O)O)C(=O)O
- InChIKey
- XEABSBMNTNXEJM-UHFFFAOYSA-N
- Polar surface area
- 118 Ų
- H-bond donors
- 2
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Research
118 papers- Propagermanium: a nonspecific immune modulator for chronic hepatitis B.Journal of gastroenterology · 2003
- Propagermanium as a Novel Therapeutic Approach for the Treatment of Endothelial Dysfunction in Type 2 Diabetes.International journal of molecular sciences · 2024
- Potentials of C-C motif chemokine 2-C-C chemokine receptor type 2 blockers including propagermanium as anticancer agents.Cancer science · 2019
- Propagermanium, a CCR2 inhibitor, attenuates cerebral ischemia/reperfusion injury through inhibiting inflammatory response induced by microglia.Neurochemistry international · 2019
- Antagonizing CCR2 With Propagermanium Leads to Altered Distribution of Macrophage Subsets and Favorable Tissue Remodeling After Myocardial Infarction in Mice.Cardiovascular therapeutics · 2025
via PubMed
Wikidata facts
- Subclass of
- organogermanium compound
- Mass
- 341.8850082599999
Show 2 more facts
- chemical formula
- C₆H₁₀Ge₂O₇
- canonical SMILES
- C(C[Ge](=O)O[Ge](=O)CCC(=O)O)C(=O)O
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Propagermanium (INN), also known by a variety of other names including bis(2-carboxyethylgermanium) sesquioxide and 2-carboxyethylgermasesquioxane, is an organometallic compound of germanium that is sold as an alternative medicine. It is a polymeric compound with the formula ((HOOCCH2CH2Ge)2O3)n.
The compound was first synthesized in 1967 at the Asai Germanium Research Institute in Japan. It is a water-soluble organogermanium compound used as raw material in nutritional supplements. The compound displays low toxicity in studies with rats.
Excerpted from Wikipedia’s “propagermanium” article, available under the CC BY-SA 4.0 licence.