Structure via PubChem · Public domain (PubChem)
fenquizone
Sign in to saveFenquizone (INN) is a diuretic, part of the class of low-ceiling sulfonamide diuretics. Fenquizone is used primarily in the treatment of oedema and hypertension.
In the Vinony graph
Within Vinony's link graph, fenquizone is referenced by 74 other articles, and connects out to collecting duct system, medication and ethanol.
It sits within the topics Chemical pages without DrugBank identifier, Chloroarenes and Drugs with no legal status.
Its subject is documented across 5 Wikipedia language editions.
Chemical data
- Formula
- C14H12ClN3O3S
- Molecular weight
- 337.8 g/mol
- IUPAC name
- 7-chloro-4-oxo-2-phenyl-2,3-dihydro-1H-quinazoline-6-sulfonamide
- SMILES
- C1=CC=C(C=C1)C2NC3=CC(=C(C=C3C(=O)N2)S(=O)(=O)N)Cl
- InChIKey
- DBDTUXMDTSTPQZ-UHFFFAOYSA-N
- XLogP
- 1.8
- Polar surface area
- 110 Ų
- H-bond donors
- 3
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- cardiovascular disease
via ChEMBL · EBI
Research
15 papers- Single-dose pharmacokinetics of fenquizone in healthy volunteers.Arzneimittel-Forschung · 1985
- On the pharmacological actions of a diuretic, fenquizone, with particular reference to its site of action.The Journal of pharmacy and pharmacology · 1981
- Clinical pharmacokinetics of some newer diuretics.Clinical pharmacokinetics · 1987
- [Fenquizone in the medium term treatment of essential hypertension. Double-blind comparison with chlorthalidone and placebo].Minerva medica · 1981
- Gas-liquid chromatographic evaluation of fenquizone in biological samples for pharmacokinetic investigations.Journal of chromatography · 1983
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 337.029
Show 4 more facts
- Commons category
- Fenquizone
- chemical formula
- C₁₄H₁₂ClN₃O₃S
- canonical SMILES
- C1=CC=C(C=C1)C2NC3=CC(=C(C=C3C(=O)N2)S(=O)(=O)N)Cl
- subject has role
- diuretic
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Fenquizone (INN) is a diuretic, part of the class of low-ceiling sulfonamide diuretics. Fenquizone is used primarily in the treatment of oedema and hypertension.
==See also== Quinethazone Metolazone
Excerpted from Wikipedia’s “fenquizone” article, available under the CC BY-SA 4.0 licence.