Skip to content
carumonam

Structure via PubChem · Public domain (PubChem)

EntityQ5047478· pop 12· linked from 185 articles

Also known as (Z)-carumonam

Carumonam (INN) is a monobactam antibiotic. It is very resistant to beta-lactamases, which means that it is more difficult for bacteria to break down using β-lactamase enzymes.

Chemical data

Formula
C12H14N6O10S2
Molecular weight
466.4 g/mol
IUPAC name
2-[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-[[(2S,3S)-2-(carbamoyloxymethyl)-4-oxo-1-sulfoazetidin-3-yl]amino]-2-oxoethylidene]amino]oxyacetic acid
SMILES
C1=C(N=C(S1)N)/C(=N/OCC(=O)O)/C(=O)N[C@H]2[C@H](N(C2=O)S(=O)(=O)O)COC(=O)N
InChIKey
UIMOJFJSJSIGLV-JNHMLNOCSA-N
XLogP
-1.4
Polar surface area
291 Ų
H-bond donors
5
H-bond acceptors
14
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule
Indications
bacterial disease

via ChEMBL · EBI

Wikidata facts

Mass
466.021283
Show 3 more facts
chemical formula
C₁₂H₁₄N₆O₁₀S₂
canonical SMILES
C1=C(N=C(S1)N)C(=NOCC(=O)O)C(=O)NC2C(N(C2=O)S(=O)(=O)O)COC(=O)N
isomeric SMILES
C1=C(N=C(S1)N)/C(=N/OCC(=O)O)/C(=O)N[C@H]2[C@H](N(C2=O)S(=O)(=O)O)COC(=O)N
Sources (2)

via Wikidata · CC0

~1 min read

Encyclopedic overview

1 sections
Contents
  • References

Carumonam (INN) is a monobactam antibiotic. It is very resistant to beta-lactamases, which means that it is more difficult for bacteria to break down using β-lactamase enzymes.

== References ==

Excerpted from Wikipedia’s “carumonam” article, available under the CC BY-SA 4.0 licence.