provirus
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A provirus is a virus genome that is integrated into the DNA of a host cell. In the case of bacterial viruses (bacteriophages), proviruses are often referred to as prophages. However, proviruses are distinctly different from prophages and these terms should not be used interchangeably. Unlike prophages, proviruses do not excise themselves from the host genome when the host cell is stressed.
Research
8,915 papers- t-RNA mediates provirus deletion in HIV-infected cells.Retrovirology · 2025
- [Provirus and diseases].Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine · 2001
- Transcriptional and Epigenetic Regulatory Mechanisms Affecting HTLV-1 Provirus.Viruses · 2016
- In vivo, in vitro, and in silico analysis of methylation of the HIV-1 provirus.Methods (San Diego, Calif.) · 2011
- Retroviruses in foreign species and the problem of provirus silencing.Gene · 2000
via PubMed
Article · Italiano
Un provirus è un genoma virale che si è integrato nel DNA della cellula ospite, in modo tale che quest'ultima non venga distrutta ma, allorché si duplica, lo trasmetta alle cellule figlie. Fra gli esempi noti di provirus si annoverano i profagi e i retrovirus. Questi ultimi quando penetrano in una cellula ospite trascrivono il proprio RNA in DNA utilizzando la transcriptasi inversa; il DNA ottenuto verrà poi integrato nel genoma della cellula ospite mediante una integrasi.
Abstract from DBpedia / Wikipedia · CC BY-SA