RAB13
Sign in to saveAlso known as GIG4, RAB13, member RAS oncogene family
Ras-related protein Rab-13 is a protein that in humans is encoded by the RAB13 gene.
Gene data
RAB13- Name
- RAB13, member RAS oncogene family
- Type
- protein-coding
- Aliases
- GIG4
This gene is a member of the Rab family of small G proteins and plays a role in regulating membrane trafficking between trans-Golgi network (TGN) and recycling endosomes (RE). The encoded protein is involved in the assembly of tight junctions, which are components of the apical junctional complex (AJC) of epithelial cells. The AJC plays a role in forming a barrier between luminal contents and the underlying tissue. Additional functions associated with the protein include endocytic recycling of occludin, regulation of epithelial cell scattering, neuronal regeneration and regulation of neurite outgrowth. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 12. [provided by RefSeq, Jan 2013].
via MyGene.info
Gene · Ensembl
RAB13, member RAS oncogene family
- Symbol
- RAB13
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:153,981,617-153,986,382
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 113882
- exact match
- identifiers.org/ncbigene/5872
- genomic end
- 153958834
- genomic start
- 153981617
- cytogenetic location
- 1q21.3
Sources (3)
via Wikidata · CC0
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Article
2 sectionsContents
- References
- Further reading
Ras-related protein Rab-13 is a protein that in humans is encoded by the RAB13 gene.
The RAB13 gene is a member of the Rab family of small G proteins and plays a role in regulating membrane trafficking between trans-Golgi network (TGN) and recycling endosomes (RE).